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Interactions

A. Top Drug-Drug Interactions:

1.Nitrates (e.g., nitroglycerin, isosorbide dinitrate): Cialis and nitrates both lower blood pressure. Taking them together can cause a significant and potentially life-threatening drop in blood pressure (hypotension), leading to dizziness, fainting, or even heart attack or stroke. It is contraindicated to use Cialis with nitrates or recreational "poppers" (amyl nitrites).

2.Alpha-blockers (e.g., prazosin, terazosin, tamsulosin): Both Cialis and alpha-blockers relax blood vessels, which can lead to excessive blood pressure reduction when used together. This may result in dizziness, fainting, or orthostatic hypotension (a sudden drop in blood pressure when standing). If needed, your doctor may adjust the dosage or recommend spacing the medications.

3.Other antihypertensive drugs (e.g., atenolol, propranolol, enalapril, lisinopril): Cialis can enhance the blood-pressure-lowering effects of these medications. While this interaction is usually less severe than with nitrates or alpha-blockers, it can still cause dizziness or fainting in sensitive individuals. Close monitoring of blood pressure is recommended.

Other Drug-Drug interactions:

  • Ketoconazole, itraconazole (used to manage fungal infection)
  • Protease inhibitors (used to manage HIV infection) Ex. ritonavir, lopinavir
  • Phenobarbital, phenytoin, carbamazepine (medicines used for fits)
  • Rifampicin, erythromycin, clarithromycin (medicines used for bacterial infections)
  • Other medicines used to improve blood flow to the penis (Ex. sildenafil)

B. Drug-Food Interactions:

Cialis (tadalafil) can interact with certain foods and beverages, potentially altering its effectiveness or increasing the risk of side effects. Here are the key drug-food interactions to be aware of:

  1. Grapefruit and Grapefruit Juice: Grapefruit can increase the levels of tadalafil in your blood by interfering with its metabolism. This may amplify side effects, such as headaches, dizziness, or low blood pressure. Avoid consuming grapefruit or grapefruit juice while taking Cialis.
  2. Alcohol: Drinking alcohol with Cialis can enhance the blood pressure-lowering effects of the medication, leading to symptoms like dizziness, lightheadedness, or fainting. Limiting alcohol intake is recommended while using Cialis.
  3. High-Fat Meals: While Cialis can be taken with or without food, consuming it with a high-fat meal may delay its onset of action. Opt for lighter meals if rapid effectiveness is needed.
  4. Caffeine: Though not a direct interaction, combining Cialis with high caffeine intake might worsen side effects like headaches or increase heart rate in sensitive individuals.
Desc code for synergism: Tadalafil can enhance the blood pressure-lowering effects of one or more medications.
  • Grapefruit and Grape Juice: Grapefruit can increase the levels of tadalafil by inhibiting the enzymes adenosodiesterase (ACE) and inosine-guanine DNA glycosylhydrolase (IGDG), respectively. If you take Cialis with a grapefruit juice, consuming it with itraconazole can enhance side effects like headaches or dizziness.
  • : Though not a direct interaction, combining Cialis with a alcohol intake schedule in conjunction with taking Cialis with may enhance side effects like headaches or dizziness in eligible individuals.
  • : While tadalafil can be taken with or without food, consuming it with high tamsulosin meal may worsen side effects like headaches or increase heart rate in sensitive individuals.
  • How Cialis Works

    Cialis works by relaxing the blood vessels in your penis, allowing blood to flow into your penis when you get sexually excited. This helps you achieve and maintain a firmer erection.

    Cialis comes in a gel form. It is made of an active ingredient called tadalafil, which works by enhancing blood flow to the penis. This can increase the sensitivity and blood flow to the penis.

    Cialis has a similar effect to Viagra. The effects of the medication are similar to those of Viagra, with fewer side effects.

    Cialis Dosages

    Cialis (Tadalafil) is available in different strengths, as prescribed by a healthcare professional.

    The recommended starting dose is one tablet once a day, taken as needed. Your doctor will determine the appropriate dosage for you based on your medical history and response to treatment.

    Cialis is only available on prescription from your primary healthcare provider.

    The dosage for Cialis depends on your condition and response to the medication. The following dosages are available:

    • Daily Cialis:Initial dosage is one tablet (20mg) taken as needed, once a day. It can be increased to three tablets (25mg) or reduced to one tablet (20mg) every 4 to 6 hours for best results.
    • Progesterone:Daily Cialis is a progesterone that helps with your natural reproductive system. It is a natural hormone that works by improving blood flow to the penis.
    • Cialis Daily:Cialis is a daily oral medication that provides you with an additional benefit in case of an erection or during sex, like during sexual activity.
    • Lifestyle Changes: Regular physical activity, such as walking, cycling, or swimming, can increase the effectiveness of Cialis and help you feel more relaxed and relaxed. Some lifestyle changes may help improve your overall health and prevent potential side effects.

    Please note that Cialis comes in different strengths, so your doctor will determine the appropriate strength for you based on your medical condition and your response to the treatment. It’s important to talk to your doctor about any lifestyle changes you are taking before starting Cialis to ensure it works as intended.

    Cialis Side Effects

    The most common side effects of Cialis are:

    • Headaches
    • Nausea
    • Flushing (redness or warmth in the face, neck, or chest)
    • Dizziness
    • Visual disturbances
    • Back pain
    • Muscle aches
    • Muscle aches or back pain
    • Indigestion
    • Upset stomach
    • Stuffy nose
    • Trouble sleeping

    If any of these side effects persist or worsen, contact your doctor immediately. They may be able to adjust the dosage or recommend alternative treatments.

    Cialis Drug Interactions

    Cialis interacts with certain medications, including:

    • Nitrates
    • Alpha-blockers
    • Blood pressure medications
    • Antifungal medications
    • Antibiotics

    You should not use Cialis if you have certain medical conditions, especially if you take any medications, including prescription and over-the-counter medicines. Consult your doctor before using Cialis.

    As with any drug product, there may be side effects. Generally, patients who experience side effects usually get them within 12 to 24 hours after taking Tadalafil. Side effects usually resolve on their own within 48 hours.

    Most common Tadalafil side effects

    • Headache
    • Indigestion
    • Back pain
    • Muscle pain
    • Flushing
    • Stuffy nose

    Some more serious side effects have been reported. While rare, it is important to stop taking Tadalafil and contact a doctor right away if any of the following occur:

    • An erection will not go away (priapism). If you have an erection that lasts longer than 4 hours, get medical help right away. If not treated right away, priapism can permanently damage the penis.
    • Sudden vision loss in one or both eyes. Sudden vision loss can be a sign of a serious eye problem called non-arteritic anterior ischemic optic neuropath (NAION).
    • Sudden hearing decrease or hearing loss. Some may also have ringing in the eyes (tinnitus) or dizziness.

    For a complete list of possible side effects,.

    Possible drug interactions

    Some drugs/medications may interact with Tadalafil. You should not take Tadalafil if you are taking nitrates (such as nitroglycerin tablets or patches) because the combination of these with Tadalafil could significantly lower blood pressure and lead to fainting or even death. Additionally, do not take Tadalafil if you are taking Cisapride, other ED medications (e.g. Viagra), Adcirca, or Riociguat.

    On your intake form, please be sure to provide AgelessRx with all medications, herbs, non-prescription drugs, or dietary supplements you use. Also be sure to report if you smoke, drink alcohol, or use illegal drugs, as some may interact with your medication.

    For a complete list of possible drug interactions,.

    Other important safety information

    Patients who have a condition called “left ventricular outlet obstruction” from valvular problems or heart muscle enlargement may get side effects such as fainting or light-headedness. Because patients with recent heart attacks or stroke, heart pains (angina), heart failure, uncontrolled blood pressure or uncontrolled irregular heart beats, severe liver disease, and retinal eye problems have not been studied, Tadalafil (Cialis) is not recommended for these patients. There may be rare occurrences of priapism or painful, prolonged erections. This is a serious condition that requires immediate medical attention. Patients should seek prompt medical attention if their erection lasts longer than four hours.

    After taking a single tablet, Tadalafil can remain in the body for up to two days. It can remain longer if patients have problems with their kidneys or liver, or they are taking certain other medications.

    Note:All information included on this page is a summary. It may not cover all possible information. If you have questions about this medication, talk to a doctor, pharmacist, or health care provider.

    Note: The above statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

    This product is not intended to interact with medications containing nitrates or any other drugs you take.

    We take responsibility for our patients.​

    Warnings

    Tadalafil is not intended to cure erectile dysfunction. However, tell your doctor if erection problems happen and ask if you can change your medication. Ask a doctor before you prescribed this medication to you.

    ED Medication Information

    For most patients, a normal erection will last 4 to 6 hours. Patients may get an erection anytime during the day, with or without sexual stimulation, and most patients get one in the first few hours. Patients who have already experienced an erection after four hours or more hours most often get one within four hours.

    Pfizer Inc. (NYSE: PFE):says it is pleased to announcethat it has received final approval from the US Food and Drug Administration (FDA) for theCialis®®in 20 mg, 40 mg, 60 mg and 80 mg tablets.

    Cialis® is a non-hormonal, oral phosphodiesterase type 5 (PDE5) inhibitor used to treat erectile dysfunction and pulmonary arterial hypertension (PAH). It works by helping to increase blood flow to the penis, thereby enabling a man to achieve and maintain an erection. Cialis is approved by the Food and Drug Administration (FDA) for use in men with erectile dysfunction.

    in 20 mg, 40 mg, 60 mg and 80 mg tablets is indicated for the treatment of erectile dysfunction in men with PAH orin men with erectile dysfunctionThe tablets are scored for accurate placement and should be swallowed whole with water. If required, the tablet should be swallowed whole with a full glass of water. The tablet may be split, dissolved or chewed. If taken with meals, it should be swallowed whole and not broken, crushed and chewed to avoid stomach irritation. If you are unsure if taking Cialis® for ED will affect your ability to get and maintain an erection, please consult your healthcare professional.

    in 20 mg, 40 mg, 60 mg and 80 mg tablets is indicated for the treatment of PAH or erectile dysfunction in men with PAH or erectile dysfunction. The tablets may be scored for accurate placement and should be swallowed whole with a full glass of water. If necessary, the tablet should be swallowed whole and not broken, crushed and chewed to avoid stomach irritation.

    in 20 mg, 40 mg, 60 mg and 80 mg tablets is indicated for the treatment of pulmonary arterial hypertension (PAH) and is contraindicated in patients with a known hypersensitivity to the active ingredient.

    in 20 mg, 40 mg, 60 mg and 80 mg tablets is indicated for the treatment of erectile dysfunction and is contraindicated in patients with a known hypersensitivity to tadalafil and sildenafil.

    says it is pleased to offer Cialis® (Tadalafil) for the treatment of erectile dysfunction in men with PAH or

    The information provided on this page reflects information provided by pharmaceutical companies and is not a substitute for professional medical advice. Always seek the advice of your physician or other qualified health provider with any questions you may have regarding a medical condition. Never disregard or delay seeking medical advice, especially if you have a history of heart failure, high blood pressure, liver or kidney disease, or other serious underlying conditions. If you think you are or intend to make a significant difference to your health, consult with your healthcare provider.

    This document provides general information about the use of PFE by physicians. It does not contain all available information about PFE. Physicians should be aware that this information may be useful in different patient populations. It is recommended that medical professionals, including physicians, educate themselves about the use of PFE in their practice. Before using this medication, tell your doctor or pharmacist if you are allergic to PFE, any other medications, or any of the ingredients in this medication. If you are allergic to any of the ingredients in this medication, tell your doctor or pharmacist promptly.

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